Impact of mammography and adjuvant therapy on U.S. breast cancer mortality (1975-2000)
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Impact of mammography and adjuvant therapy on U.S. breast cancer mortality (1975-2000) collective results from the Cancer intervention and surveillance modeling network by

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Published by Oxford University Press in Bethesda, MD .
Written in English


  • Breast -- Cancer,
  • Breast -- Cancer -- Mortality,
  • Cancer -- Adjuvant treatment,
  • Breast -- Radiography

Book details:

Edition Notes

SeriesJournal of the National Cancer Institute -- 2006, no. 36
ContributionsFeuer, Eric J, National Cancer Institute (U.S.), National Cancer Institute (U.S.). Statistics Research and Applications Branch
LC ClassificationsRC280.B8 I46 2006
The Physical Object
Paginationvi, 126 p. :
Number of Pages126
ID Numbers
Open LibraryOL15592849M

Download Impact of mammography and adjuvant therapy on U.S. breast cancer mortality (1975-2000)


Breast Cancer Working Group provides estimates of the contributions of screening mammography and adjuvant treatment to the reduction in the rate of death from breast cancer among U.S. women.   Good IOMs are relevant for screening, with its early cancer detection and the subsequent steps, eventually leading to a reduction in breast cancer mortality. For the impact of adjuvant therapy, an IOM analysis is not interesting because it involves only survival time, with diagnosis of distant metastases as the only possible by: 6. Breast cancer mortality reduction associated with ITS was 21% in both the case-control and cohort analyses, but the impact of attendance was marginally greater in the case-control analysis (36% vs.   An often cited JNCI monograph on the topic included reports of the results of attempts during – to model relative contributions of screening and adjuvant therapy to the observed breast cancer mortality decline between and 5 The overall conclusion was that 15% (range 8–23%) of the mortality decrease was due to mammography and 19% (range: 12–21%) was due to adjuvant therapy Cited by:

Adjuvant systemic therapy has been shown to be effective in reducing breast cancer mortality. The additional effect of mammography screening remains uncertain, in particular for women aged 40–49 ye. Introduction In the past decades, mortality due to breast cancer has declined considerably in Switzerland and other developed countries. The reasons for this decline remain controversial as several factors occurred almost simultaneously, including important advances in treatment approaches, breast cancer awareness and the introduction of mammography . The use of mammography as a means of early detection has been shown to reduce breast cancer mortality by % among those popu­ lations in which it is utilized. The use of adjuvant systemic treatment in appropriate patients provides a similar (and additional) reduction in breast cancer mortality.   A comprehensible way of communicating information on benefits and harms of mammography screening is presented in Figure 1: among 1, women who start screening at age 50 and are screened for 20 years, 2 to 3 will avoid dying from breast cancer and women will have at least one false positive test, 30 will undergo a biopsy, 3 will be diagnosed with an interval cancer, and breast cancer .

  29% (Victorian treatment survey proportion of all women aged 50 or more years with early breast cancer who received adjuvant chemotherapy) × 85% ( National treatment survey proportion of all women with early breast cancer) × 20% (EBCTCG: adjuvant chemotherapy reduction in mortality . The impact of mammography and adjuvant therapy on U.S. breast cancer mortality (): collective results from the Cancer Intervention and Surveillance Modeling Network. [Eric J Feuer; . Breast cancer is the most commonly diagnosed cancer type in women, accounting for aro deaths in the United States in [].Most patients with breast cancer are diagnosed at an early stage (%) [], largely as a result of widespread mammography screening standard of care for these patients is lumpectomy or mastectomy plus lymph node sampling followed by adjuvant.   Post-surgery treatments such as chemo or radiotherapy, also known as adjuvant therapy, are measures taken to protect patients against cancer recurrence. One type of adjuvant therapy.